发明名称 |
Prodrugs of betulinic acid derivatives for the treatment of cancer and HIV. |
摘要 |
A composition and method of preventing or inhibiting tumor growth and, more particularly, of treating a malignant tumor, using prodrugs of plant-derived compounds and derivatives is disclosed. In the method, a composition containing betulinic acid or a betulinic acid derivative is administered in a prodrug form to release betulinic acid or a betulinic acid derivative in vivo at the tumor site. |
申请公布号 |
ZA200301269(B) |
申请公布日期 |
2003.11.03 |
申请号 |
ZA20030001269 |
申请日期 |
2003.02.17 |
申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS ADVANCED LIFE SCIENCES INC. |
发明人 |
JOHN M. PEZZUTO;JEROME W II KOSMEDER;ZE-QI XU;NIAN EN. ZHOU |
分类号 |
A61K31/565;A61K;A61K31/56;A61P;A61P1/00;A61P1/02;A61P11/00;A61P13/08;A61P15/00;A61P17/00;A61P21/00;A61P25/00;A61P31/18;A61P35/00;C07B53/00;C07B61/00;C07J;C07J1/00;C07J63/00 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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