发明名称 SYSTEMIC MARKER FOR MONITORING ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIONS OF THERAPEUTIC AGENTS
摘要 A diagnostic method of monitoring anti-inflammatory and/or antioxidant actio ns of therapeutic agents comprises determining the level of at least one system ic marker indicative of inflammation or oxidation in a bodily sample taken from a subject at base line or following administration of the therapeutic agent. T he marker includes at least one of MPO activity, MPO mass, select MPO-generated oxidation products, and combinations thereof. The level of the systemic mark er is compared with a predetermined value to monitor the anti-inflammatory and/ or antioxidant actions of the therapeutic agent.
申请公布号 CA2481941(A1) 申请公布日期 2003.10.30
申请号 CA20032481941 申请日期 2003.04.17
申请人 THE CLEVELAND CLINIC FOUNDATION 发明人 HAZEN, STANLEY L.
分类号 C12Q1/28;(IPC1-7):C12Q1/28 主分类号 C12Q1/28
代理机构 代理人
主权项
地址