| 发明名称 |
Use of IL-18 inhibitors. |
| 摘要 |
The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of liver injury. The invention further relates to the use of IL-18 inhibitors in the preparation of a medicament for treatment and/or prevention of arthritis, in particular rheumatoid arthritis. In addition to this, the invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of inflammatory bowel diseases, in particular of Crohn's disease and ulcerative colitis. |
| 申请公布号 |
ZA200205471(B) |
申请公布日期 |
2003.10.29 |
| 申请号 |
ZA20020005471 |
申请日期 |
2002.07.09 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. |
发明人 |
YOLANDE CHVATCHKO;CHARLES DINARELLO;CHRISTINE PLATER-ZYBERK;SANTER VAN DEVENTER;MENACHEM RUBINSTEIN;DANIELA NOVICK;SOO-HYUN KIM |
| 分类号 |
A61K;A61K31/00;A61K35/12;A61K38/17;A61K38/21;A61K39/35;A61K39/395;A61K48/00;A61P;A61P1/04;A61P1/16;A61P19/02;A61P37/02;C12N;C12N15/63 |
主分类号 |
A61K |
| 代理机构 |
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