METHODS FOR ASSESSING THE RISK OF NON-INSULIN-DEPENDENT DIABETES MELLITUS BASED ON ALLELIC VARIATIONS IN THE 5'-FLANKING REGION OF THE INSULIN GENE AND BODY FAT

摘要

The invention features methods for determining the risk of development of non-insulin dependent diabetes mellitus (NIDDM or type II diabetes) in a subject by examining both the insulin HphI locus and the body fat value of the patient. In related aspects, the invention features methods for diagnosing a subtype of NIDDM, as well as methods to facilitate rationale therapy and maintenance of NIDDM patients.