| 摘要 |
Alterations to a host cell protein form a set of specific alterations which may be deployed to then limit a trial and error process in order to arrive at an Anti-Protein targeted to a host cell protein. The invention dictates regulation of monomers, multimers, oligomeric subunits and oligomers, or proteins by changing their form and function sufficiently, to yield a new set of interaction rules which closely resemble the rules followed by naturally occurring monomers, multimers, oligomeric subunits oligomers and proteins. This Anti-Protein contains highly specific alterations, which render the ultimate presence and sufficient concentration of these compositions to yield predictably different interaction, structure and function for the cell and which incorporate the necessary coding for transcription, translation and sufficient concentrated production for these Anti-Proteins, to enable regulation of a particular cellular function, such as viral replication. |
