| 摘要 |
<p>It is intended to develop remedies for treating pemphigus by administering a CD40L antagonist to a patient suffering from pemphigus such as pemphigus vulgaris or pemphigus foliaceus, and preventives for preventing the onset of pemphigus by administering a CD40L antagonist preventively. CD40L antagonists such as an anti-CD40L antibody, which inhibits the interaction between a receptor CD40L mediating the adhesion-dependent helper effecter function on T cell surface and a receptor CD40 on antigen-presenting cell surface, are efficacious as remedies and preventives for pemphigus.</p> |
