METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE
摘要
The present invention relates to the treatment, diagnosis, and prophylactic prevention of Alzheimer's disease. More specifically, the present invention relates to methods and compositions for preventing the endocytosis and cellular internalization of integral membrane amyloid precursor protein (APP) and its subsequent catabolism by blocking or interfering with the association or binding of APP with the very low density lipoprotein receptor.
申请公布号
WO03086300(A2)
申请公布日期
2003.10.23
申请号
WO2003US10938
申请日期
2003.04.09
申请人
THE GENERAL HOSPITAL CORPORATION;AMERICAN RED CROSS;HYMAN, BRADLEY, T.;STRICKLAND, DUDLEY;KINOSHITA, AYAE;WHELAN, CHRISTA;REBECK, WILLIAM, G.
发明人
HYMAN, BRADLEY, T.;STRICKLAND, DUDLEY;KINOSHITA, AYAE;WHELAN, CHRISTA;REBECK, WILLIAM, G.