| 发明名称 |
Substituted amine derivatives and methods of use |
| 摘要 |
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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| 申请公布号 |
US2003195230(A1) |
申请公布日期 |
2003.10.16 |
| 申请号 |
US20020046622 |
申请日期 |
2002.01.10 |
| 申请人 |
CHEN GUOQING;ADAMS JEFFREY;BEMIS JEAN;PIETRO LUCIAN DI;DOMINGUEZ CELIA;ELBAUM DANIEL;GERMAIN JULIE;HUANG QI;KIM JOSEPH L.;OUYANG XIAOHU;PATEL VINOD F.;SMITH LEON M.;TASKER ANDREW;XI NING;XU SHIMIN;YUAN CHESTER CHENGUANG;CROGHAN MICHAEL;KIM TAE-SEONG |
发明人 |
CHEN GUOQING;ADAMS JEFFREY;BEMIS JEAN;PIETRO LUCIAN DI;DOMINGUEZ CELIA;ELBAUM DANIEL;GERMAIN JULIE;HUANG QI;KIM JOSEPH L.;OUYANG XIAOHU;PATEL VINOD F.;SMITH LEON M.;TASKER ANDREW;XI NING;XU SHIMIN;YUAN CHESTER CHENGUANG;CROGHAN MICHAEL;KIM TAE-SEONG |
| 分类号 |
A61K31/00;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/4745;A61K31/496;A61K31/5377;A61K31/538;A61P1/04;A61P1/16;A61P3/04;A61P7/06;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P15/00;A61P17/02;A61P17/06;A61P19/02;A61P27/02;A61P27/06;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/08;A61P43/00;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;(IPC1-7):A61K31/443;A61K31/454;A61K31/44;A61K31/403;A61K31/402;A61K31/401;A61K31/165;C0743/02;C0741/02 |
主分类号 |
A61K31/00 |
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