发明名称 NOVEL COMPOUNDS
摘要 Compounds of formula (I) wherein: R1 represents substituted or unsubstituted heteroaryl; Y represents -(CRnaRnb)n-; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 0 to 5;R2 represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R3 and R4 each independently represent hydrogen or C1-6alkyl; R7 represents hydrogen or C1-6alkyl; R8 represents hydrogen or C1-6alkyl;and salts and solvates thereof;are CCR3 antagonists and are thus indicated to be useful in therapy.
申请公布号 WO03082861(A2) 申请公布日期 2003.10.09
申请号 WO2003EP03335 申请日期 2003.03.27
申请人 GLAXO GROUP LIMITED;ANCLIFF, RACHAEL, ANN;COOK, CAROLINE, MARY;ELDRED, COLIN, DAVID;GORE, PAUL, MARTIN;HARRISON, LEE, ANDREW;HAYES, MARTIN, ALISTAIR;HODGSON, SIMON, TEANBY;JUDD, DUNCAN, BRUCE;KEELING, SUZANNE, ELAINE;LEWELL, XIAO, QING;MILLS, GAIL;ROBERTSON, GRAEME, MICHAEL;SWANSON, STEPHEN;WALKER, ANDREW, JOHN;WILKINSON, MARK 发明人 ANCLIFF, RACHAEL, ANN;COOK, CAROLINE, MARY;ELDRED, COLIN, DAVID;GORE, PAUL, MARTIN;HARRISON, LEE, ANDREW;HAYES, MARTIN, ALISTAIR;HODGSON, SIMON, TEANBY;JUDD, DUNCAN, BRUCE;KEELING, SUZANNE, ELAINE;LEWELL, XIAO, QING;MILLS, GAIL;ROBERTSON, GRAEME, MICHAEL;SWANSON, STEPHEN;WALKER, ANDREW, JOHN;WILKINSON, MARK
分类号 C07D413/12;A61K31/5377;A61P11/02;A61P11/06;A61P29/00;A61P43/00;C07D231/12;C07D253/06;C07D257/04;C07D271/06;C07D307/34;C07D333/38;C07D413/14;C07D417/12 主分类号 C07D413/12
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