发明名称 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE
摘要 The invention provides novel compounds of the Formula (I) that stimulate rat es of glucose oxidation in myocardial cells wherein W, Cyc, p, , X, Z, R, K-, R , R1, R2, R3,R4, I and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose Oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.< /SDOAB>
申请公布号 CA2480557(A1) 申请公布日期 2003.10.09
申请号 CA20032480557 申请日期 2003.03.31
申请人 THE UNIVERSITY OF ALBERTA 发明人 LOPASCHUK, GARY DAVID;VEDERAS, JOHN CHRISTOPHER;DYCK, JASON ROLAND
分类号 A61K31/13;A61K31/164;A61K31/215;A61P3/08;C07C69/74;C07C69/753;C07C69/757;C07C217/08;C07C219/12;C07C233/60;C07C233/63 主分类号 A61K31/13
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