RECOMBINANT CHIMERIC PROTEIN FOR THE TARGET DELIVERY OF DNA TO EUKARIOTIC TARGET CELLS

摘要

The invention relates to biotechnology, gene engineering, the microbiological and medical industries. The aim of said invention is to develop a recombinant carrier protein for address delivering a plasmid DNA to selected target cells. The inventive recombinant protein comprises three structure functional domains integrated into the following single polypeptide chain: a DNA-binding domain, a toxin and streptavidine . Said invention also involves the construction of the gene of a recombinant fused protein carrier by combining coding sequences of said three functional domains and isolating and purifying said recombinant protein.