POLYNUCLEOTIDES ENCODING NOVEL TWO SPLICE VARIANTS OF A HUMAN CELL SURFACE PROTEIN WITH IMMUNOLOGOBULIN FOLDS, BGS5G AND BGS5I

摘要

The present invention provides novel polynucleotides encoding BGS-5G, and BGS-5I polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-5G, and BGS-5I polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.