发明名称 |
Inhibitors of caspase-3-mediated cleavage of essential ventricular myosin light chain |
摘要 |
The invention discloses use of a peptide containing an essential ventricular myosin light chain type 1 (vMLC1) amino acid sequence, which is functional as cleavage site for caspase-3, in the screening for a compound for the treatment of chronic or acute cardiovascular disease. Further, screening methods for inhibitors of the caspase-3-mediated cleavage of vMLC1 are disclosed.
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申请公布号 |
EP1351057(A1) |
申请公布日期 |
2003.10.08 |
申请号 |
EP20020007569 |
申请日期 |
2002.04.03 |
申请人 |
PROCORDE GMBH |
发明人 |
MORETTI, ALESSANDRA;HOLTHOFF, HANS-PETER;UNGERER, MARTIN;MUENCH, GOETZ;LAUGWITZ, KARL-LUDWIG |
分类号 |
G01N33/68;(IPC1-7):G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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