发明名称 COMPOSTOS UTEIS PARA O TRATAMENTO DE ALERGIAS E DOENCAS UNFLAMATORIAS
摘要 Novel compounds of Formula (I) <CHEM> are described herein. These compounds inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production. The compounds of the present invention are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV and are therefore useful in the treatment of disease states in need of mediation or inhibition thereof.
申请公布号 PT919544(E) 申请公布日期 2003.09.30
申请号 PT19980204466T 申请日期 1993.03.05
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 SIEGFRIED B. CHRISTENSEN
分类号 A61K31/215;A61K31/275;A61K31/41;A61K31/42;A61K31/4245;A61K31/425;A61K31/433;A61P11/00;A61P29/00;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07C43/205;C07C43/225;C07C43/23;C07C61/28;C07C69/003;C07C69/712;C07C69/75;C07C69/753;C07C237/30;C07C255/46;C07C259/06;C07C259/08;C07C303/30;C07C309/65;C07C311/15;C07C319/12;C07C323/60;C07D257/04;C07D271/06;C07D271/10;C07D285/12 主分类号 A61K31/215
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