| 摘要 |
The invention is directed to a process for modifying a water soluble polymer, said process comprisingmodifying a polymer containing amine groups, by reacting at least one of said amine groups with activated ester, said ester being the reaction product of a carboxyl activator and the carboxyl group of a molecule R-COOH, said R-group being a functional group, to produce a reaction mixture containing a polymer, said polymer containing at least one amide group;subjecting said reaction mixture to at least ion exchange chromatography to purify said reaction mixture, said purification comprising at least partly removing the said reaction product, and/or carboxyl activator.
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