摘要 |
Disclosed are compounds of the formula I, and pharmaceutically acceptable salts and prodrugs thereof, wherein W, R<1 >, R<2>, R<7>, R<8>, R<9> and R<10> are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds. |
申请人 |
ARRAY BIOPHARMA, INC;WALLACE, ELI, M.;LYSSIKATOS, JOSEPH, P.;HURLEY, BRIAN, T.;MARLOW, ALLISON, L. |
发明人 |
WALLACE, ELI, M.;LYSSIKATOS, JOSEPH, P.;HURLEY, BRIAN, T.;MARLOW, ALLISON, L. |