METHODS OF INDUCING DIFFERENTIATION OF STEM CELLS INTO A SPECIFIC CELL LINEAGE

摘要

The present invention relates to methods of inducing differentiation of stem cells into a specific cell lineage, particularly prostate cell lineage. In particular, the invention relates to in vitro and/or in vivo methods of inducing differentiation of stem cells into a specific cell lineage. The invention also relates to methods of producing and recovering differentiated stem cells of a specific cell lineage. The invention also includes differentiated stem cells and cell lineages produced by the methods of the present invention. In one aspect of the present invention there is provided a method of inducing differentiation of a stem cell into a specific cell lineage, particularly prostate cell lineages, the method including:culturing a stem cell in vitro and/or in vivo in the presence of a tissue sample and/or extracellular medium of a tissue sample, under conditions that induce differentiation of the stem cell into a specific cell lineage, wherein the differentiated stem cell is the same cell type as the tissue sample.