| 发明名称 |
Processes for preparing clarithromycin polymorphs |
| 摘要 |
The present invention relates to processes for converting clarithromycin Form I to clarithromycin Form II, which include slurrying clarithromycin the Form I in water. The present invention also relates to processes for the preparation of clarithromycin Form II by converting erythromycin A to clarithromycin and thereafter converting clarithromycin Form I to clarithromycin Form II by slurrying.
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| 申请公布号 |
US6624292(B2) |
申请公布日期 |
2003.09.23 |
| 申请号 |
US20000736446 |
申请日期 |
2000.12.15 |
| 申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
LIFSHITZ IGOR;AVRUTOV ILYA;SCHWARTZ EDI;MASARWA BASEM |
| 分类号 |
A61K;A61K31/70;A61K31/7048;A61P31/04;C07H;C07H1/00;C07H17/08;(IPC1-7):C07H1/00 |
主分类号 |
A61K |
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