| 摘要 |
PURPOSE: Provided is a physiological active material of Bisboralactin which exhibits strong toxicity with respect to cancer cells of leukemia, lung cancer, uterine carcinoma, melanoma, large intestine cancer and central nervous system cancer, and works as a multi-purpose anticancer agent. CONSTITUTION: A physiological active material is a compound expressed by the formula 1 where R1 and R3 being identical with or different from each other are hydrogen and methyl or ethyl, respectively, and R2 and R4 being identical with or different from each other are hydrogen, and methyl, ethyl, propyl or isopropyl, respectively. The compound is extracted by culturing the Actinomycetes of Streptomyces sp., isolating mycelium from the culture, and purifying it.
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