发明名称 |
POLYNUCLEOTIDE SEQUENCING METHOD |
摘要 |
A method for determining the sequence of a polynucleotide comprising the steps of (i) contacting a polynucleotide processive enzyme immobilised in a fixed position, with a target polynucleotide under conditions sufficient to induce enzyme activity; (ii) detecting an effect consequent on the interaction of the enzyme and the polynucleotide, wherein the effect is detected by measurement of a non-linear optical signal or a linear signal coupled to a non-linear signal. |
申请公布号 |
WO02095070(A3) |
申请公布日期 |
2003.09.18 |
申请号 |
WO2002GB02345 |
申请日期 |
2002.05.20 |
申请人 |
MEDICAL BIOSYSTEMS LITD.;DENSHAM, DANIEL, HENRY |
发明人 |
DENSHAM, DANIEL, HENRY |
分类号 |
G01N21/65;C12M1/34;C12N11/00;C12N15/09;C12Q1/48;C12Q1/68;G01N13/16;G01N21/27 |
主分类号 |
G01N21/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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