发明名称 |
INTERFERON BETA-LIKE MOLECULES FOR TREATMENT OF STROKE |
摘要 |
The present invention relates to use of interferon beta-like polypeptides for treatment of stroke or transient ischemic attach in a primate, preferably in a human. More particularly, the interferon beta-like polypeptides differs from the amino acid sequence of wild-type human IFNB SEQ ID NO:2 in that at least one glycosylation site, preferably at least one in vivo N-glycosyltaion site has been introduced. Optionally the interferon beta-like polypeptides are PEGylated. |
申请公布号 |
WO03075944(A2) |
申请公布日期 |
2003.09.18 |
申请号 |
WO2003DK00127 |
申请日期 |
2003.02.28 |
申请人 |
MAXYGEN APS;H. LUNDBECK A/S;GLAZER, STEVEN;SAGER, THOMAS |
发明人 |
GLAZER, STEVEN;SAGER, THOMAS |
分类号 |
C12N15/09;A61K38/21;A61P9/10;C07K14/52 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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