发明名称 |
Peptides and peptide analogues designed from a diabetes-associated autoantigen, and methods for their use in the treatment and prevention of diabetes |
摘要 |
The present invention relates to peptides and peptide analogues designed from a human pancreatic islet beta cell autoantigen GAD65. In particular, it relates to antagonistic peptides and peptide analogues that antagonize autoimmune T cell activation in response to GAD65. The invention also relates to methods of using such peptides and peptide analogues for the treatment and prevention of type I diabetes or pre-diabetes.
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申请公布号 |
US2003176351(A1) |
申请公布日期 |
2003.09.18 |
申请号 |
US20030403980 |
申请日期 |
2003.03.28 |
申请人 |
NEPOM GERALD T.;MASEWICZ SUSAN;NEPOM BARBARA S. |
发明人 |
NEPOM GERALD T.;MASEWICZ SUSAN;NEPOM BARBARA S. |
分类号 |
C12N15/09;A61K38/00;A61K38/11;A61K39/00;A61P3/10;A61P43/00;C07K7/04;C12N9/88;(IPC1-7):A61K38/10;C07K7/06;C07K7/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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