发明名称 |
Benzopyrazone compounds, compositions thereof, and methods of treatment therewith |
摘要 |
Benzopyranone compounds having the following structure:wherein R1, X, Y and n are as defined here, are disclosed. The compounds of formula (I), wherein R1 is H, can be prepared by demethylation of the corresponding phenolic methyl ether. The compounds are useful for treating a bone-resorbing disease, cancer, arthritis or an estrogen-related condition such as breast cancer, osteoporosis and endometriosis.
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申请公布号 |
US6620838(B1) |
申请公布日期 |
2003.09.16 |
申请号 |
US20020125965 |
申请日期 |
2002.04.19 |
申请人 |
SIGNAL PHARMACEUTICALS, INC. |
发明人 |
MCKIE JEFFREY A.;BHAGWAT SHRIPAD S.;RENAUD JOHANNE;MISSBACH MARTIN |
分类号 |
C07D311/16;(IPC1-7):A61K31/402;C07D405/10 |
主分类号 |
C07D311/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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