Compositions and methods for modulation of immune responses

摘要

The present invention relates to a novel mechanism for modulation of immune response. More closely, the present invention relates to modulation of CD94/NKG2 receptor function by HLA-E+bound peptides causing either inhibition or absence of inhibition of said receptors. In a preferred embodiment the invention relates to HLA-E binding hsp (heat shock protein) 60 peptides.