| 摘要 |
PROBLEM TO BE SOLVED: To provide an aldose reductase inhibitor which prevents and/or treats apoptosis-associated diseases. SOLUTION: The aldose reductase inhibitor depresses apoptosis and is effective for prevention and/or treatment of apoptosis-associated diseases, for example, dementia such as senile dementia of Alzheimer type, etc., cerebrovascular disease, neurodegenerative disease, AIDS, AIDS-related disease, HIV, HTLV- related diseases such as diseases, adult T cell leukemia, leukemic reticuloendotheliosis, myelopathia, respiratory disorder, arthropathy, uveitis, etc., collagenosis such as systemic lupus erythematosus, chronic rheumatism, etc., and ulcerous colitis, etc. COPYRIGHT: (C)2003,JPO
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