发明名称 |
BIARYL COMPOUND AND USE THEREOF |
摘要 |
PROBLEM TO BE SOLVED: To provide a new biaryl compound having melanocortin receptor agonist action or antagonist action. SOLUTION: The compound is represented by formula (I) [wherein rings A and B are each a 6-membered aromatic ring which may further be substituted; X is CONR<SP>4</SP>, SO<SB>2</SB>NR<SP>4</SP>or CH<SB>2</SB>NR<SP>4</SP>(R<SP>4</SP>is hydrogen atom, an optionally substituted hydrocarbon group or the like) or the like; Y is a spacer or the like having 1-12 number of atoms; Z is CONR<SP>6</SP>(R<SP>6</SP>is hydrogen atom or an optionally substituted hydrocarbon group or optionally substituted heterocyclic group), CO or the like; R<SP>1</SP>is an optionally substituted amino group or the like; R<SP>2</SP>is an optionally hydrocarbon group or the like; R<SP>3</SP>is an optionally hydrocarbon group or the like; R<SP>5</SP>is an optionally hydrocarbon group or the like] or its salt. COPYRIGHT: (C)2003,JPO
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申请公布号 |
JP2003252857(A) |
申请公布日期 |
2003.09.10 |
申请号 |
JP20020377946 |
申请日期 |
2002.12.26 |
申请人 |
TAKEDA CHEM IND LTD |
发明人 |
CHO NOBUO;ASO KAZUYOSHI;ENDO SATOSHI;KANZAKI NAOYUKI;SASAKI SATOSHI |
分类号 |
C07D211/58;A61K31/4468;A61K31/4525;A61K31/454;A61K31/4545;A61K31/496;A61P3/00;A61P3/04;A61P15/10;A61P25/18;A61P29/00;A61P31/18;A61P43/00;C07D401/06;C07D401/12;C07D405/06;(IPC1-7):C07D211/58;A61K31/446;A61K31/452 |
主分类号 |
C07D211/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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