发明名称 BIOMEDICAL IMPLANT SURFACES WITH OSTEOGENIC PROPERTIES
摘要 The invention relates to a device with a surface covered by a thin film or monolayer of a poly (ethylene glycol)-grafted copolymer exhibiting osteogenic properties, defined in an osteoblastic cell culture test as a surface that increases the expression of growth factor TFG-beta1, the expression of hormone PGE2 and/or the expression of mineralization marker osteocalcin by at least a factor of 2 in comparison to the corresponding control surface consisting of either unmodified substrate surface or of tissue-culture polystyrene (TCPS).
申请公布号 WO03072156(A1) 申请公布日期 2003.09.04
申请号 WO2002CH00125 申请日期 2002.02.28
申请人 EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH OBERFLAECHENTECHNIK;SIMPSON, JAMES, P.;DENZER, ALAIN, J.;BOYAN, BARBARA, D.;SCHWARTZ, ZVI, D.;TOSATTI, SAMUELE;SPENCER, NICHOLAS, D.;TEXTOR, MARCUS 发明人 SIMPSON, JAMES, P.;DENZER, ALAIN, J.;BOYAN, BARBARA, D.;SCHWARTZ, ZVI, D.;TOSATTI, SAMUELE;SPENCER, NICHOLAS, D.;TEXTOR, MARCUS
分类号 A61L27/34;(IPC1-7):A61L27/34 主分类号 A61L27/34
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