OPHTHALMIC ANTIBIOTIC DRUG FORMULATIONS CONTAINING A CYCLODEXTRIN COMPOUND AND CETYL PYRIDINIUM CHLORIDE

摘要

There is provided a pharmaceutical composition suitable for topical administration to an eye, the composition comprising (a) an antibiotic antibiotic drug, for example linezolid, in a therapeutically or prophylactically effective drug concentration, (b) as a solubilizing agent, a pharmaceutically acceptable cyclodextrin compound in a concentration sufficient to maintain the drug in solution at such a drug concentration, an d (c) as a preservative, cetyl pyridium chloride. The composition is particularly useful for the treatment and/or prevention of eye infections du e to gram positive bacteria.