发明名称 |
CHROMATOGRAPHIC METHOD FOR DETERMINING THE MOLECULAR WEIGHT DISTRIBUTION OF AN ANIONIC POLYSACCHARIDE |
摘要 |
Methods for determining the molecular weight distribution in a sample of an anionic polysaccharide is provided. The methods generally include: providing a sample of an anionic polysaccharide with an average molecular eight in the range of from 0.05 to 10 MDa; applying the sample to an anion-exchange chromatography column so as to immobilize the polysaccharide to the column; eluting the immobilized polysaccharide while recording a chromatogram of the amount of polysaccharide eluted as a function of time; and determining the molecular weight distribution in the polysaccharide sample through analysis of the chromatogram. Also provided is use of anion-exchange chromatography for the determination of molecular weight distribution in a sample of an anionic polysaccharide with an average molecular weight in the range of from 0.05 to 10 MDa.
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申请公布号 |
WO03071264(A1) |
申请公布日期 |
2003.08.28 |
申请号 |
WO2003SE00274 |
申请日期 |
2003.02.19 |
申请人 |
BIOVITRUM AB;KARLSSON, GOERAN |
发明人 |
KARLSSON, GOERAN |
分类号 |
G01N30/88;B01J41/20;G01N30/02;G01N30/26;G01N30/86;G01N30/96;G01N33/44;(IPC1-7):G01N30/02;B01D15/08;B01J41/06 |
主分类号 |
G01N30/88 |
代理机构 |
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地址 |
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