发明名称 alphavbeta3 integrin inhibitors.
摘要 The invention describes novel compounds of the formula I which are biologically active as ligands of integrin alphavbeta3in which X, Y, Z, R<1>, R<2>, R<4 >and R<5 >are as defined in claim 1, and their physiologically acceptable salts and solvates.
申请公布号 ZA200202284(B) 申请公布日期 2003.08.27
申请号 ZA20020002284 申请日期 2002.03.20
申请人 MERCK PATENT GMBH. 发明人 ALFRED JONCZYK;OLIVER SCHADT;SIMON GOODMAN
分类号 C07D233/48;A61K31/4164;A61K31/4168;A61K31/4184;A61K31/44;A61K31/4402;A61K31/505;A61P7/02;A61P9/10;A61P11/00;A61P13/12;A61P17/02;A61P17/06;A61P19/10;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P43/00;C07D213/74;C07D233/60;C07D233/88;C07D235/30;C07D239/42 主分类号 C07D233/48
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