Nucleotide incorporating enzyme variants having improved properties including the ability to utilize non-natural or rare nucleotide analogues in the synthesis of polynucleotides are provided. Methods for producing such nucleotide incorporating enzyme variants are provided, as are kits and integrated systems including the nucleotide incorporating enzyme variants.
申请公布号
WO0210358(A3)
申请公布日期
2003.08.21
申请号
WO2001US24181
申请日期
2001.07.31
申请人
MAXYGEN, INC.;RAILLARD, SUN, AI;WELCH, MARK;NESS, JON