COMPOSITIONS AND METHODS FOR PROMOTING LIPID MOBILIZATION, GLYCOGEN MOBILIZATION, OR BOTH, IN HUMANS

摘要

The invention provides methods of using polypeptide compounds based on the structures of insect peptides of the adipokinetic hormone family in humans for a variety of purposes, including mobilization of lipids and glycogen, inhibition of protein, lipid, and RNA synthesis, and enhancement of muscle contractility. The compositions and methods described in the application are useful, for example, for modulating human body weight, inducing weight loss, and alleviating glycogen storage disorders. The invention also includes screening methods for identifying other compounds having similar activities in humans.