| 发明名称 |
METHOD OF TREATING AND PREVENTING BONE LOSS |
| 摘要 |
Methods of treating and preventing bone loss and/or enhancing bone formation are disclosed. The methods utilize 15-lipoxygenase inhibitors. These molecules can be delivered alone or in combination with agents which inhibit bone resorption or additional agents that regulate calcium resorption from bone or enhances bone accumulation. The invention additionally provides methods of diagnosing a predisposition to bone loss. |
| 申请公布号 |
WO03066048(A2) |
申请公布日期 |
2003.08.14 |
| 申请号 |
WO2003EP01033 |
申请日期 |
2003.02.03 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;THE GOVERNMENT OF THE UNITED STATES;OREGON HEALTH & SCIENCE UNIVERSITY |
发明人 |
ALLARD, JOHN, DAVID;KLEIN, ROBERT, FREDERICK;PELTZ, GARY, ALLEN |
| 分类号 |
G01N33/50;A61K31/167;A61K31/192;A61K31/404;A61K31/407;A61K31/56;A61K31/663;A61K38/18;A61K38/23;A61K38/27;A61K38/30;A61K45/00;A61K45/06;A61P1/02;A61P19/00;A61P19/02;A61P19/08;A61P19/10;C12N9/99;C12N15/09;C12Q1/02;C12Q1/26;C12Q1/68;G01N33/15 |
主分类号 |
G01N33/50 |
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