NON-INVASIVE DIAGNOSTIC IMAGING TECHNOLOGY FOR MITOCHONDRIA USING RADIOLABELED LIPOPHILIC SALTS
摘要
The invention provides a series of lipophilic phosphonium cations (PhCs) labeled with 18F for non-invasive assessment of DELTA&PSgr;m, lipophilic ammonium cation analogs of the PhCs, and methods of using same for imaging and detection of mitochondrial-related pathologies in patients using PET or SPECT.
申请公布号
WO03065882(A2)
申请公布日期
2003.08.14
申请号
WO2003US03740
申请日期
2003.02.06
申请人
THE JOHNS HOPKINS UNIVERSITY;MADAR, IGAL;RAVERT, HAYDEN, T.;DANNALS, ROBERT;SCHEFFEL, URSULLA, A.;FROST, JAMES, J.
发明人
MADAR, IGAL;RAVERT, HAYDEN, T.;DANNALS, ROBERT;SCHEFFEL, URSULLA, A.;FROST, JAMES, J.