METHOD AND NUCLEIC ACIDS FOR THE DIFFERENTIATION OF ASTROCYTOMA, OLIGOASTROCYTOMA AND OLIGODENDROGLIOMA TUMOR CELLS

摘要

The present invention relates to the chemically modified nucleic acid sequences of genomic DNA, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for the characterization, classification, differentiation, grading, staging, treatment and diagnosis of oligodendrogliomas, astrocytomas and oligoastrocytomas.