发明名称 PROCESS FOR THE PREPARATION OF MESYLATES OF PIPERAZINE DERIVATIVES
摘要 The invention relates to mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine ring and the mesylate formation are combined in a single reaction step. The invention relates to the mesylate of compounds of the formula wherein X is a bicyclic heterocyclic phenyl group and Y is methyl, ethyl (optionally substituted with fluorine), cycloalkyl (3-7C)methyl, benzyl or m-phenyl benzyl.
申请公布号 BG108090(A) 申请公布日期 2003.08.13
申请号 BG20030108090 申请日期 2003.08.13
申请人 SOLVAY PHARMACEUTICALS B.V. 发明人 VAN AAR MARCEL;SCHOUTEN STEFANUS;ZORGDRAGER JAN;HESLINGA MICHIEL
分类号 C07D263/58 主分类号 C07D263/58
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