发明名称 |
SHAPED BODY COMPRISING AN AMPHIPHILIC OUTER PHASE AND A LIPOPHILIC INNER PHASE |
摘要 |
<p>Water-dispersible or water-soluble polymers, particularly those of the family of compounds comprising the poloxamers or the polyesters or amphiphilic agents (emulsifiers), and also lipophilic materials are dispersed by melting the components at suitable temperatures with admixture of pharmaceutically active substances by mechanical precedures, i.e. a lipophilic dispers phase is distributed in a hydrophilic continuous polymer phase to form a stable dispersion. By controlled cooling, curing, and storage followed by high-pressure molding at defined temperatures and operating pressures there are produced, in addition to other types of shaped bodies, dispersed polymeric fatty sticks distinguished by particularly good fracture strength, flexibility, and variable time-specific dimensional stability.</p> |
申请公布号 |
EP1220656(B1) |
申请公布日期 |
2003.08.13 |
申请号 |
EP20000974391 |
申请日期 |
2000.10.13 |
申请人 |
ROGASCH, RAINER;FISSELER, FRIEDRICH;SCHMIEDING, MARC |
发明人 |
ROGASCH, RAINER;FISSELER, FRIEDRICH;SCHMIEDING, MARC |
分类号 |
A61K47/34;A61K9/00;A61K9/02;A61K9/16;A61K9/20;A61K9/48;A61K31/755;A61K45/00;A61K47/06;A61K47/10;A61K47/14;A61K47/44;A61P17/02;(IPC1-7):A61K9/02 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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