发明名称 N-[(substituted five-membered di-or triaza diunsaturated ring)carbonyl] guanidine derivatives for the treatment of ischemia
摘要 NHE-1 inhibitors, methods of using such NHE-1 inhibitors and pharmaceutical compositions containing such NHE-1 inhibitors. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.
申请公布号 US2003149043(A1) 申请公布日期 2003.08.07
申请号 US20020315369 申请日期 2002.12.09
申请人 PFIZER INC. 发明人 HAMANAKA ERNEST S.;GUZMAN-PEREZ ANGEL;MULARSKI CHRISTIAN J.;RUGGERI ROGER B.;WESTER RONALD T.
分类号 C07D249/04;A61K31/415;A61K31/4155;A61K31/416;A61K31/4184;A61K31/4192;A61K31/4196;A61K31/428;A61K31/433;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/4709;A61K31/4725;A61K31/495;A61K31/498;A61K31/502;A61K31/517;A61P3/10;A61P9/00;A61P9/06;A61P9/10;A61P9/12;A61P13/12;A61P19/04;A61P35/00;A61P41/00;A61P43/00;C07D231/14;C07D231/56;C07D249/06;C07D249/10;C07D401/04;C07D403/04;C07D403/10;C07D405/04;C07D409/04;C07D413/04;C07D417/04;C07D521/00;(IPC1-7):A61K31/517;A61K31/470 主分类号 C07D249/04
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