The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein family, CMR1, which is involved in modulation of the perception of cold sensations and pain. The invention further relates to methods for identifying and using agents that modulate cold responses and pain responses stimulated by cold via modulation of CMR1 and CMR1-related signal transduction.
申请公布号
WO03064602(A2)
申请公布日期
2003.08.07
申请号
WO2003US02318
申请日期
2003.01.27
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;JULIUS, DAVID;MCKEMY, DAVID, D.;NEUHAUSSER, WERNER, M.
发明人
JULIUS, DAVID;MCKEMY, DAVID, D.;NEUHAUSSER, WERNER, M.