发明名称 |
PROTEIN S FUNCTIONAL ASSAY |
摘要 |
The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant tissue factor (pTF or rTF), purified natural or synthetic phospholipid (pPL or sPL) and activated protein C (APC) or protein C activator (PCA). The clotting time is then measured and compared to a standard curve or a normal control.
|
申请公布号 |
WO02052276(A9) |
申请公布日期 |
2003.07.31 |
申请号 |
WO2001US50338 |
申请日期 |
2001.12.19 |
申请人 |
INSTRUMENTATION LABORATORY COMPANY |
发明人 |
DAI, YONG;YE, BIQING;CHEN, KUI;BRUGUERA, PAU;TANG, SHAMAY |
分类号 |
C07K14/745;G01N33/86;(IPC1-7):G01N33/86 |
主分类号 |
C07K14/745 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|