| 发明名称 |
Novel compounds and a novel process for their preparation |
| 摘要 |
The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
|
| 申请公布号 |
US2003144275(A1) |
申请公布日期 |
2003.07.31 |
| 申请号 |
US20020317183 |
申请日期 |
2002.12.12 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
FAGNOU KEITH;LAUTENS MARK |
| 分类号 |
C07D295/08;A61K31/055;A61K31/085;A61K31/09;A61K31/136;A61K31/18;A61K31/222;A61K31/225;A61K31/235;A61K31/27;A61K31/277;A61K31/36;A61K31/40;A61K31/4035;A61K31/404;A61K31/4453;A61K31/47;A61K31/472;A61K31/4725;A61P25/16;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/02;A61P43/00;C07B61/00;C07C41/01;C07C41/03;C07C43/196;C07C43/23;C07C43/253;C07C43/295;C07C45/71;C07C49/84;C07C67/24;C07C69/013;C07C69/16;C07C69/732;C07C205/38;C07C215/44;C07C215/86;C07C217/52;C07C255/54;C07C271/24;C07C271/28;C07C311/20;C07C311/21;C07D209/08;C07D209/48;C07D215/06;C07D217/04;C07D295/096;C07D295/12;C07D295/135;C07D317/70;C07D493/08;C07D493/18;C07F7/08;C07F7/18;(IPC1-7):A61K31/542;A61K31/538;A61K31/497;A61K31/519;A61K31/454;A61K31/470;A61K31/445;A61K31/402;C07F7/02;C07D417/02;C07D413/02;C0743/02;C0741/02 |
主分类号 |
C07D295/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
