摘要 |
<p>Clinically efficacious compounds which are usable as remedies for various diseases in which poly(ADP-ribose) polymerase (PARP) participates, in particular, inflammatory diseases such as rheumatoid arthritis. Quinoxaline derivatives having a carbamoyl group at the 5-position and specific substituent(s) at the 2- and/or 3-positions, in particular, compounds having a cyclic hydrocarbon group or a heterocyclic group substituted by, for example, Y1-Y2R4 at the 3-position or pharmaceutically acceptable salts thereof.</p> |