| 发明名称 |
PYRIMIDINE DERIVATIVES AS RHO-KINASE INHIBITORS |
| 摘要 |
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumo r growth, treating erectile dysfunction, and treating other indications mediat ed by Rho-kinase, e.g., coronary heart disease.
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| 申请公布号 |
CA2473510(A1) |
申请公布日期 |
2003.07.31 |
| 申请号 |
CA20032473510 |
申请日期 |
2003.01.23 |
| 申请人 |
BAYER PHARMACEUTICALS CORPORATION |
发明人 |
BENNABI, SAMIR;HATOUM-MOKDAD, HOLIA;NAGARATHNAM, DHANAPALAN;DUMAS, JACQUES;FEURER, ACHIM;PLUEMPE, HANS;WANG, CHUNGUANG;BOYER, STEPHEN |
| 分类号 |
A61K31/505;A61K31/506;A61K31/517;A61K31/519;A61P7/02;A61P9/10;A61P9/12;A61P9/14;A61P11/06;A61P15/10;A61P19/10;A61P25/00;A61P25/28;A61P27/06;A61P35/00;A61P43/00;C07B57/00;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D409/14;C07D413/12;C07D413/14;C07D471/04;(IPC1-7):C07D401/12 |
主分类号 |
A61K31/505 |
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