发明名称 Bactericidal/permeability-increasing protein (BPI) deletion analogs
摘要 Novel BPI deletion analogs are provided that consist of amino acid residues 10 through 193 of mature human BPI wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.
申请公布号 US6599880(B1) 申请公布日期 2003.07.29
申请号 US20000579403 申请日期 2000.05.25
申请人 XOMA CORPORATION 发明人 HORWITZ ARNOLD;CARROLL STEPHEN F.;BURKE DAVID
分类号 C12N15/09;A01N37/18;A61K38/00;A61K38/16;A61P31/04;C07H21/04;C07K14/00;C07K14/47;C12N5/00;C12N5/10;C12N9/48;C12N15/31;C12N15/74;C12P21/02;C12P21/06;C12R1/91;(IPC1-7):A61K38/00 主分类号 C12N15/09
代理机构 代理人
主权项
地址