The present invention relates to novel, soluble, recombinant variants RANKL (Receptor Actovator of Nuclear Factor -kB ligand) proteins, which may be expressed solubly in E. coli, variants that act as RANKL antagonists, and methods for generating the same.
申请公布号
WO03059281(A2)
申请公布日期
2003.07.24
申请号
WO2003US00393
申请日期
2003.01.06
申请人
XENCOR;DESJARLAIS, JOHN, R.;HUBERT, RENE, S.;YAZAL, JAMAL, EL
发明人
DESJARLAIS, JOHN, R.;HUBERT, RENE, S.;YAZAL, JAMAL, EL
