发明名称 Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives
摘要 The present invention is the synthesis of a series of 1,5-dichloro-9(10H)-anthracenones bearing O-linked and N-linked substituents in the 10-position. These compounds were evaluated for their ability to inhibit the growth of the human oral epidermoid carcinoma cells (KB cell line), human cervical carcinoma cells of ME 180 (GBM 8401) and Chinese hamster ovary cells (CHO), respectively. In addition, redox property of the compounds for inhibition of lipid peroxidation in model membranes was determined.
申请公布号 US6596774(B1) 申请公布日期 2003.07.22
申请号 US20010965774 申请日期 2001.09.27
申请人 HUANG HSU-SHAN 发明人 HUANG HSU-SHAN
分类号 A61K31/122;C07C49/755;C07C225/20;(IPC1-7):A61K31/12;C07C50/16 主分类号 A61K31/122
代理机构 代理人
主权项
地址