| 发明名称 |
Tenascin-C nucleic acid ligands |
| 摘要 |
Methods are described for the identification and preparation of nucleic acid ligands to tenascin-C. Included in the invention are specific RNA ligands to tenascin-C identified by the SELEX method. Further included in the invention are methods for detecting the presence of a disease condition in a biological tissue in which tenascin-C is expressed.
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| 申请公布号 |
US6596491(B2) |
申请公布日期 |
2003.07.22 |
| 申请号 |
US20010854662 |
申请日期 |
2001.05.14 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
HICKE BRIAN;WARREN STEPHEN;PARMA DAVID;GOLD LARRY |
| 分类号 |
G01N33/53;A61K31/7088;A61K38/00;A61K45/00;A61K47/48;A61P9/10;A61P17/06;A61P35/00;C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07K14/00;C12N9/12;C12N15/09;C12N15/10;C12N15/115;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/531;G01N33/532;G01N33/535;G01N33/566;G01N33/569;G01N33/58;G01N33/60;G01N33/68;G01N33/76;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/53 |
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