发明名称 3(5)-AMINO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS.
摘要 <p>Compounds which are 3-amino-pyrazole derivatives represented by formula (I) wherein R is C<SUB>3</SUB>-C<SUB>6 </SUB>cycloalkyl group optionally substituted by a straight or branched C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl or arylalkyl group; R<SUB>1 </SUB>is a straight or branched C<SUB>1</SUB>-C<SUB>6 </SUB>alkyl, C<SUB>2</SUB>-C<SUB>4 </SUB>alkenyl, cycloalkyl, cycloalkenyl, heterocyclyl, aryl, arylalkyl, arylcarbonyl, aryloxyalkyl or arylalkenyl group, each of which may be optionally further substituted as indicated in the description; or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases or neurodegenerative diseases.</p>
申请公布号 MXPA02001498(A) 申请公布日期 2003.07.21
申请号 MX2002PA01498 申请日期 2000.05.05
申请人 PHARMACIA & ITALIA S.P.A. 发明人 WARPEHOSKI, MARTHA, A.
分类号 A61K31/415;A61K31/4155;A61K31/427;A61K31/4439;A61K31/4709;A61K31/506;A61K45/06;A61P9/10;A61P11/00;A61P13/08;A61P13/12;A61P17/06;A61P17/14;A61P19/02;A61P25/28;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07D231/16;C07D231/40;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D409/14;C07D417/12;(IPC1-7):A61K31/415 主分类号 A61K31/415
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