| 摘要 |
FIELD: chemical technology, pharmacy. SUBSTANCE: invention relates to the improved method for preparing the known anti-inflammatory substance mometasone furoate (I). (I) is prepared by direct esterification of 17-hydroxyl group of mometasone using 2-furoyl chloride in the presence of tertiary amine and inert solvent, preferably, dichloromethane without preliminary protection of free 11-hydroxyl group. For removal of formed enolfuroate additional treatment with hydrochloric acid is carried out. EFFECT: improved preparing method. 8 cl
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