发明名称 Triterpene derivatives and remedies for liver diseases
摘要 A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof:wherein R1 represents a hydroxyl group, arylmethyloxy, lower alkoxy, or lower alkanoyloxy, R2 represents lower alkyl, lower alkenyl, -CH2OR5, formyl, -COOR6, or -CH2N(R7)R8, or R1 and R2 may combine with each other to form -O-C(R9)R10-O-CH2-, R3 and R4, which may be the same or different represent a hydrogen atom, a hydroxyl group, lower alkyl, lower alkenyl, aryl, hydroxymethyl, -N(R11)R12, formyl, -COOR6, or -OR13, or R3 and R4 may combine with each other to form oxo, hydroxyimino, or alkylidene and X represents O, CH2, or NH.
申请公布号 US6593364(B2) 申请公布日期 2003.07.15
申请号 US20010921983 申请日期 2001.08.06
申请人 MEIJI SEIKA KAISHA, LTD. 发明人 SASAKI KAZUE;MINOWA NOBUTO;NISHIYAMA SHOJI;KUZUHARA HIROYUKI
分类号 C07J71/00;A61K31/56;C07J53/00;C07J63/00;(IPC1-7):A61K31/215;A61K31/255;A61K31/335;A61K31/045 主分类号 C07J71/00
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